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Artistic tendencies linked to ‘schizophrenia gene’

PET scans of a schizophrenia sufferer's brain (left) and normal brain (right).

PET scans of a schizophrenia sufferer's brain (left) and normal brain (right).

New Scientist is reporting a fascinating study suggesting a statistical correlation between a gene linked to schizophrenia and creativity. The study, conducted by Szabolcs Kéri, a researcher at Semmelweis University in Budapest, Hungary:

“examined a gene involved in brain development called neuregulin 1, which previous studies have linked to a slightly increased risk of schizophrenia. Moreover, a single DNA letter mutation that affects how much of the neuregulin 1 protein is made in the brain has been linked to psychosis, poor memory and sensitivity to criticism . . .

“To determine how these variations affect creativity, Kéri genotyped 200 adults who responded to adverts seeking creative and accomplished volunteers. He also gave the volunteers two tests of creative thinking, and devised an objective score of their creative achievements, such as filing a patent or writing a book.

“People with two copies of the neuregulin 1 mutation – about 12 per cent of the study participants – tended to score notably higher on these measures of creativity, compared with other volunteers with one or no copy of the mutation. Those with one copy were also judged to be more creative, on average, than volunteers without the mutation. All told, the mutation explained between 3 and 8 per cent of the differences in creativity”.

I’m always a little sceptical of such studies, not least because of the reductive assumptions inherent in their methodology. But this research fits neatly with a number of other studies suggesting a link between mood disorders and creativity (some of which I’ve mentioned before).

You can read more at New Scientist. And while you’re there, take a minute or two to read this story about researchers turning brain scans into sound, a process which not only reveals patterns and rhythms not always visible to the eye, but also allows the “unsteady rhythms and cadences” (a lovely expression) of dysfunctions such as schizophrenia to emerge. Stranger still is the fact the music of the (hemi)spheres sounds just like early Philip Glass.
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One Comment Post a comment
  1. Nora #

    RE: The study reveals patterns and rhythms not always visible…

    Is it not a characteristic of the schizophrenic mind to see(k) patterns where there are none?

    LOL It makes sense, as the making of patterns (or stories) from the stuff of life is a mark of creativity.

    July 18, 2009

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